Supply Chain Management (SCM) is an indispensable component for E-Businesses striving for efficiency and customer satisfaction. This chapter provides an in-depth exploration of three pivotal aspects of SCM: Inventory Management Systems, Order Fulfillment Systems, and Logistics and Transportation Management. Dive into the functionalities and benefits of systems like Zoho Inventory, ShipStation, and C.H. Robinson’s TMC. Each segment details how they ensure product availability, streamline order processes, and optimize transportation routes. Embrace these insights to transform your E-Commerce operations, ensuring seamless integration, cost reduction, and enhanced customer experiences