This paper proposes the use of an enterprise architecture methodology known as the Systemic Enterprise Architecture Methodology to determine the relevance of EA in addressing the business-IT alignment. A construct that characterized EA was developed based on review of the literature. A theoretical framework build upon the Systemic Enterprise Architecture Methodology (SEAM) was used based on a business-IT alignment market, in which supplier business systems compete to provide a value to an adopter business system. Data was empirically gathered based on survey respondents who are concerned with the adoption, planning and implementation of EA in their organizations. Respondents were managers and executives representing the IT and senior level management of public and private organizations in Malaysia. The data collected was then analyzed based on the following factors: (1) EA business issues; (2) EA environment; (3) EA governance; and (4) EA methods, tools and frameworks. Comparative analysis was carried out based on the four factors to examine the trend and status of EA adoption and implementation in Malaysia vis-à-vis the international scenario. Statistical analysis was used to validate the SEAM, which was found to be relevant in addressing the business-IT alignment.