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Enterprise Architecture (EA) governance serves as a crucial framework, enabling organizations to consistently adhere to a myriad of legal and regulatory requirements pertinent to their industry. This chapter delves deep into the relationship between EA governance and regulatory compliance, highlighting how the former provides structured processes and controls to synchronize an organization’s IT, business operations, and regulatory obligations. By mapping out regulations, instituting robust compliance controls, and routinely assessing regulatory impacts, organizations can ensure they operate within legal boundaries. Additionally, through practical examples, the chapter illustrates the real-world application of this framework across sectors like healthcare and finance. Moreover, the text offers strategies to seamlessly integrate compliance within the EA governance structure, emphasizing continuous improvement and employee engagement. By perusing this comprehensive information, readers will gain insights into optimizing their governance practices, ensuring compliance, and mitigating associated risks.